Lives listing with initial: S
- Seytres, Joseph de, marquis de Caumont (born 1688–died 1745), French archaeologist, bibliophile, collector, collector, academician, historian
- Sèze, Romain de (born 1748–died 1828), French lawyer, academician
- Shackleton, Richard (born 1726–died 1792), Irish schoolteacher
- Shaen, Sir James (died 1695), Irish politician, member of Parliament, civil servant, landowner, academician
- Shallcross, Joseph (flourished 1789), American Quaker, merchant, civil servant, spy
- Shank, Alexander (flourished 1797–1801), [unknown nationality] merchant
- Shank, Henry (flourished 1799–1801), [unknown nationality] merchant
- Sharman, Lieutenant-colonel — (flourished 1770–1790), Irish militia officer, politician
- Sharp, Abraham (born 1653–died 1742), English mathematician, scientific-instrument maker
- Sharp, Anne (born c. 1777–died after 1851), English governess, tutor, author, playwright
- Sharp, Buccleuch (flourished c. 1786), Scottish printer
- Sharp, Granville (born 1735–died 1813), English abolitionist
- Sharp, John (died 1793), American army officer
- Sharp, Richard (born 1759–died 1835), English politician, member of Parliament, wit, academician
- Sharpe, Horatio (born 1718–died 1790), English civil servant, colonial governor
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